Sweta Kumari
M.Pharm Student (Pharmacology), Jaipur College of Pharmacy, Jaipur, Rajasthan
Yogesh Kumar Sharma
Department of Pharmacology, Jaipur College of Pharmacy, Jaipur, Rajasthan
Mayank Bansal
Professor and Principal, Jaipur College of Pharmacy, Jaipur, Rajasthan, India
Abstract
Diabetes mellitus is a metabolic disorder. This review article is planned to The anti-diabetic effect of Withania Coagulans have been successfully used in Ayurvedic and other traditional formulations and found to be efficient and inexpensive as compared to synthetic drugs. It also aims to test and verify the W. coagulans fruits, showed significant inhibition on postprandial rise in hyperglycemia post-sucrose load in normoglycemic rats as well as streptozotocin-induced diabetic rats. which is comparable to the standard antidiabetic drug Glibenclamide for medical care, The present study defines the systematic evaluation and the role of minerals in glycemic potential of aqueous extract of Withania coagulans fruits in order to develop an effective and safe alternative treatment for diabetes mellitus.
These study conducted to determine the antidiabetic effect of Withania coagulans and pancreatic histological features in streptozotocin induced diabetic rat.
Keywords: Anti-Diabetic effect, Screening & Evaluation, Streptozocin, Glibenclamide, Diabetic rats.