Shivani Bhasney
PG Scholar, Institute of Pharmacy, Bundelkhand University, Jhansi, (U.P.)
Peeyush Bhardwaj
Associate Professor, Institute of Pharmacy, Bundelkhand University, Jhansi, (U.P.)
Nirmala Devi
Assistant Professor, Institute of Pharmacy, Bundelkhand University, Jhansi, (U.P.)
Abstract
The niosomal gel of the chosen formula (F2) was formulated by incorporating the niosomal dispersion in a mixture of Carbopol 974 gel base and Na-CMC. Briefly, a sufficient amount of Carbopol 974 was gradually added to water and kept for 24 h for complete hydration of polymer chains. Niosomes and liposomes have similar physical properties but differ in the chemical nature. Niosomal vesicle is formed by non-ionic surfactants whereas liposomal vesicles of lipids. Niosomes are superior to liposomes because of higher chemical stability of surfactants than lipids. This review article focuses on the concept of niosomes, advantages and disadvantages, composition, method of preparation, factors influencing the niosomal formulation and characterization, application of niosomes. Niosomes can be utilized in the treatment of several diseases like Psoriasis, leishmaniasis, cancer, migraine, Parkinson etc.
Keywords: Niosomal, liposomes, chemical. Polymer, lipids