Ram Swaroop
Research Scholar, Goenka College of Pharmacy, Lachhmangarh, Sikar, Rajasthan
Dr. Vijay Sharma
Professor, Goenka College of Pharmacy, Lachhmangarh, Sikar, Rajasthan.
Dr. N. Ravindra
Principal and Professor, Goenka College of Pharmacy, Lachhmangarh, Sikar, Rajasthan
Abstract
Mouth dissolving tablets provide patient convenience as it does not require water as well as offer faster onset of action as compared to conventional oral tablets. The objective of the present study is to formulate mouth dissolving tablet of Montelukast sodium for improved patient compliance, faster onset of action and better management of Asthma. The prepared MDT were evaluated for various parameters i.e. shape and size, weight variation, thickness, hardness, friability, wetting time, disintegration time, drug content, dissolution test, accelerated stability studies etc. The prepared tablet passed all the evaluation tests. After comparing the results , it was concluded that formulation MT9 was selected as the best formulation among all. Finally, it can be concluded that mouth dissolving tablet of Montelukast sodium can be formulated using above excipients and method that disintegrate rapidly for improved patient compliance, faster onset of action and better management of Asthma.
Key Words: Patient compliance, Asthma, Accelerated stability studies.