Main Article Content
Ajay Kumar
Research Scholar, SunRise University, Alwar, Rajasthan, India.
Shilpi Mishra
Research Scholar, SunRise University, Alwar, Rajasthan, India
Vidhi Jain
Research Scholar, SunRise University, Alwar, Rajasthan, India
Arti Pandey
Research Scholar, SunRise University, Alwar, Rajasthan, India
Dr. Manmeet Singh Saluja
Professor, SunRise University, Alwar, Rajasthan, India
Abstract
The present study aimed to determine the hepatoprotective activity of aqueous extract of Nyctanthes arbortristis bark (AQENA) using one established rat models. Four groups of rats (n=6) were givens one daily administration of 1ml/kg in 50% of v/v olive oil (negative control), 25mg/kg silymarin (positive control) and AQENA (500mg/kg) for 7 days fallowed by induction of hepatotoxicity using of carbon tetrachloride. Various parameters, such as physical parameters, biochemical parameters and microscopic analysis ware used to evaluate the hepatoprotective activity. Results indicate that bark extract would significantly support hepatoprotective activity and antioxidants activity, therefore requires in further in depth studies.
Keywords: Bark of N. arbortristis, aqueous extract, and hepatoprotective activity