U. Nisha Gopika
Department of Microbiology, Faculty of Science, Annamalai University, Annamalai Nagar, 608-002, India.
J. Tharani
Department of Microbiology, Faculty of Science, Annamalai University, Annamalai Nagar, 608-002, India.
D. Sangeetha
Department of Microbiology, Faculty of Science, Annamalai University, Annamalai Nagar, 608-002, India.
Abstract
Natural products have been a significant source of commercial medicines and drug leads. Screening of crude plants Extracts paves the way for discovery of novel Bioactive compounds, and elucidation of their Structures can open the door for new Synthetic preparations. The present study was undertaken to check the antibacterial activity of two different seed viz., Syzygium cumini and Phyllanthus acidus against clinical pathogens. Four clinical pathogens viz., Escherichia coli, Staphylococcus aureus, Streptococcus pneumoniae and salmonella typhi were procured from Department of Microbiology, RMMCH Annamalai University, Chidambaram. The Two different Seed extracts were prepared using Methanol (Syzygium cumini and Phyllanthus acidus). Among the Two tested Seeds, Jamun Seed exhibited maximum zone of inhibition (21 ±0.4mm) against Staphylococcus aureus. The minimum Antibacterial activity exhibited by Star Gooseberry Seed towards the tested bacterial pathogens.
Keywords: Syzygium cumini, Phyllanthus acidus, Clinical pathogens, Methanol extract.