A Review: Tablet Including its Formulation and Evaluation

Abstract

According to the Indian Pharmacopoeia (IP); Pharmaceutical tablets are solid, flat or biconvex dishes, unit dosage form, prepared by compressing a drug or a mixture of drugs, with or without diluents. Tablet is also defined as a compressed solid dosage form containing medicaments with or without excipients. Tablets are now the most popular dosage form, accounting for some 70% of all ethical pharmaceutical preparations produced. Pharmaceutical oral solid dosage forms have been used widely for decades mainly due to their convenience of administration and their suitability for delivery of drugs for systemic effects. A tablet contains one or more medicaments with or without suitable excipients and prepared either by molding or by compression. The excipients include diluents, binders and adhesives, disintegrants etc. Tablets vary in shape and differ greatly in size and weight depending on the amount of the medicinal substance. The ingredients must be granulated prior to compression to assure an even distribution of the active compound in the final tablet. There are two basic techniques which can be used to granulate powders for compressions into a tablet are wet granulation and dry granulation.
In this review article; tablet and its types, formulation and manufacturing processes, evaluation parameters and its defects including its packaging have been discussed.
Keywords: Types of tablets, Formulation, Manufacturing, Tablet Defects, Evaluation Parameters, Packaging.