CLINICO-PATHOLOGICAL EVALUATION OF PATIENTS OF EARLY BREAST CANCER ATTENDING TERTIARY CARE INSTITUTE: A STUDY FROM CENTRAL INDIA

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Venktesh Rewale Gaurav Gangadhar Jannawar

Abstract

Background: According to the International Agency for Research on Cancer's (IARC) World Cancer Report, cancer rates are expected to rise at an alarming rate over the world. In the year 2020, cancer rates could rise by 50%, resulting in 15 million new cases. Breast cancer is the most common cancer in women worldwide, and it is also the second greatest cause of cancer death in women (after lung cancer).
Aims and Objectives: To assess individuals with early breast cancer who are undergoing treatment at a tertiary care facility.
Materials and Method: In the current trial, a total of 100 individuals were enrolled. All of the cases were first assessed clinically. A full history of the current disease, prior history, history of risk factors (age at menarche, family history, menopausal status), and a thorough physical examination were all part of the clinical evaluation. Both the breasts and the axillae were examined and palpated during the local examination. To rule out any symptoms of distant metastases, a systemic examination was performed. The disease was clinically staged based on these findings, using the AJCC classification system. Following a clinical evaluation, the patient was subjected to diagnostic, staging, and fitness tests. FNAC or biopsy, as well as Mammography, were used as diagnostic tests. When the lump was palpable, FNAC was performed quickly, but when the mass was not palpable, a USG-guided or mammography-guided localised biopsy was performed.
Results: Seventy-one percent of the patients were between the ages of 41 and 60. Patients were found to be postmenopausal in 56 percent of cases, premenopausal in 28 percent, and perimenopausal in 16 percent. Ninety percent of the patients had two or more children, according to the findings. It's worth noting that just 28% of patients who had an early full-term pregnancy developed breast cancer, compared to 72% of women who were pregnant between the ages of 21 and 30 years.
Conclusion: As a result, we infer that patients with breast cancer who visited a tertiary care facility were multiparous, postmenopausal females between the ages of 41 and 60. Infiltrating Duct Carcinoma was the most prevalent histological type found, with tumour sizes ranging from 2 to 4 cm and grades II and III tumour types, with ER/PR positivity in 64% of patients.
Keywords: breast cancer, Infiltrating Duct Carcinoma, parity

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Rewale, V., & Jannawar, G. G. (2020). CLINICO-PATHOLOGICAL EVALUATION OF PATIENTS OF EARLY BREAST CANCER ATTENDING TERTIARY CARE INSTITUTE: A STUDY FROM CENTRAL INDIA. International Journal of Pharmaceutical and Biological Science Archive, 8(1). Retrieved from http://www.ijpba.in/index.php/ijpba/article/view/224
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